Two years later, I was able to dig up that original clump and spread it around to create many more plants, some of which I planted in a waterway where not many other plants want to grow. Research carried out using different in vitro and in … Bull. The study investigated the purified zerumbone crystals for its anti-cancer properties on human cervical cancer cell line (HeLa). Common name i: Shampoo ginger: Synonym i: Amomum zerumbet: Other names i ›Zingiber darceyi ›Zingiber darceyi H.J.Veitch ›Zingiber zerumbet (L.) Sm. It is also known to possess antioxidant and anti-inflammatory activities. Also known as bitter ginger, Z. zerumbet is traditionally found throughout Asia, where it is widely used in foods, beverages and for ornamental purposes. XI. ‘Awapuhi is pretty easy to find, as it was a canoe plant, an ancient Polynesian introduction into Hawaii. Common names for Zingiber zerumbet include … Bot. I pressure can food and was wondering if I could do the same with the awapuhi liquid. Zerumbone induces heme oxygenase-1 expression in mouse skin and cultured murine epidermal cells through activation of Nrf2, Immunomodulatory effects of zerumbone isolated from roots of Zingiber zerumbet, Calpain and reactive oxygen species targets Bax for mitochondrial permeabilisation and caspase activation in zerumbone induced apoptosis, Zerumbone suppresses phorbol ester-induced expression of multiple scavenger receptor genes in THP-1 human monocytic cells, Biomedical properties of a natural dietary plant metabolite, zerumbone, in cancer therapy and chemoprevention trials, Zerumbone, a tropical ginger sesquiterpene, ameliorates streptozotocin-induced diabetic nephropathy in rats by reducing the hyperglycemia-induced …, Zingiber zerumbet CYP71BA1 catalyzes the conversion of α-humulene to 8-hydroxy-α-humulene in zerumbone biosynthesis, Attenuation of cisplatin-induced nephrotoxicity in rats using zerumbone, Zerumbone enhances the Th1 response and ameliorates ovalbumin-induced Th2 responses and airway inflammation in mice, Antisecretory, gastroprotective, antioxidant and anti-helicobcter pylori activity of zerumbone from Zingiber Zerumbet (L.) Smith, Dietary zerumbone prevents against ultraviolet B-induced cataractogenesis in the mouse, Dietary zerumbone prevents mouse cornea from UVB-induced photokeratitis through inhibition of NF-κB, iNOS, and TNF-α expression and reduction of MDA …, Zerumbone-loaded nanostructured lipid carrier induces G2/M cell cycle arrest and apoptosis via mitochondrial pathway in a human lymphoblastic leukemia …, Zerumbone isolated from Zingiber zerumbet inhibits inflammation and pain in rats, Zerumbone suppresses IKKα, Akt, and FOXO1 activation, resulting in apoptosis of GBM 8401 cells, Molecular cloning and functional characterization of α-humulene synthase, a possible key enzyme of zerumbone biosynthesis in shampoo ginger (Zingiber zerumbet …, Zerumbone exerts a beneficial effect on inflammatory parameters of cholecystokinin octapeptide-induced experimental pancreatitis but fails to improve histology, Crystal structure of zerumbone [(E, E, E)-2, 6, 9, 9-Tetramethylcycloundeca-2, 6, 10-trien-1-one], Unprecedented olefin-dependent histidine–kinase inhibitory of zerumbone ring-opening material, Zerumbone causes Bax-and Bak-mediated apoptosis in human breast cancer cells and inhibits orthotopic xenograft growth in vivo, Optimization of SC–CO2 extraction of zerumbone from Zingiber zerumbet (L) Smith, Regression of cervical intraepithelial neoplasia by zerumbone in female Balb/c mice prenatally exposed to diethylstilboestrol: involvement of mitochondria-regulated …, Zerumbone attenuates the severity of acute necrotizing pancreatitis and pancreatitis-induced hepatic injury, Zerumbone exerts antiproliferative activity via apoptosis on HepG2 cells, Transannular cyclizations of zerumbone epoxide, High content of zerumbone in volatile oils of Zingiber zerumbet from southern India and Malaysia, Zerumbone, an electrophilic sesquiterpene, induces cellular proteo-stress leading to activation of ubiquitin–proteasome system and autophagy, Hepatoprotective action of zerumbone against paracetamol induced hepatotoxicity, Zerumbone inhibits growth of hormone refractory prostate cancer cells by inhibiting JAK2/STAT3 pathway and increases paclitaxel sensitivity, Chondroprotective effect of zerumbone on monosodium iodoacetate induced osteoarthritis in rats, Notch2 activation is protective against anticancer effects of zerumbone in human breast cancer cells, Exploring the immunomodulatory and anticancer properties of zerumbone, Abrogation of STAT3 signaling cascade by zerumbone inhibits proliferation and induces apoptosis in renal cell carcinoma xenograft mouse model, Altered cross-linking of HSP27 by zerumbone as a novel strategy for overcoming HSP27-mediated radioresistance, In vivo and In vitro Genotoxic Effects of Zerumbone, Comparative study on inhibitory activity of zerumbone and zerumbone 2, 3-epoxide on NF-κB activation and NO production, Combination of zerumbone and cisplatin to treat cervical intraepithelial neoplasia in female BALB/c mice, Remarkable synthesis and structure of allene type zerumbone, Target profiling of zerumbone using a novel cell-permeable clickable probe and quantitative chemical proteomics, Acute toxicity study of zerumbone-loaded nanostructured lipid carrier on BALB/c mice model, Synthesis of a novel inhibitor against MRSA and VRE: preparation from zerumbone ring opening material showing histidine-kinase inhibition, Synthesis of macrocyclic terpenoids by intramolecular cyclization. Like some other gingers, ‘awapuhi dies back annually to store its energy in its roots/rhizomes. 004 cone gingers.jpg 574 × 480; 104 KB. not totally sure. Zingiber zerumbet is a species of plant in the ginger family with leafy stems growing to about 1.2 m (3.9 ft) tall. I’ve seen this plant for sale at local nurseries, too. Anti-Cancer - One natural compound called zerumbone, a cyclic eleven-membered sesquiterpene, isolated from the tropical plant Zingiber zerumbet Smith that has attracted great attention recently for its potent anticancer activities in several tumor models. The rhizome has traditionally been used in medicinal applications as an anti-inflammatory, anti-diarrheal, de-wormer, and for various types of pain management. from Bangladesh, Standardized ethanol extract, essential oil and zerumbone of Zingiber zerumbet rhizome suppress phagocytic activity of human neutrophils, Abstract# 2977: Zerumbone, a sesquiterpene isolated from Zingibers zerumbet, induces Nrf2-driven heme oxygenase-1 expression in mouse skin in vivo and cultured …, Antitumor Effect of Zerumbone Isolated from Lempoyang (Zingiber Zerumbet) on Human Cervical Cancer Cells and Mouse Cervical Intraepithelial Neoplasia, EFFECTS OF DAMNACANTHAL, NORDAMNACANTHAL, BETULINIC ACID AND ZERUMBONE ISOLATED FROM LOCAL MEDICINAL PLANTS ON …. Or a address where I can buy; It originates from Asia, but can be found in many tropical countries. Phytochemistry 30(7):2391–2392 Google Scholar. 1. Zingiber ovoideum Blume. Zingiber zerumbet, ‘Awapuhi or Shampoo Ginger, is a perennial multipurpose herbaceous plant. The scientific name of the species, Zingiber spectabile, comes from two words. Zingiber zerumbet (L.) Roscoe ex Sm., Zingiberaceae, is a perennial, aromatic and tuberose plant that grows in humid locations. 1806, although many consider 1805 the year when this work was published. Love this Website? Ask a friend growing the plant for some rhizomes! The rhizome has traditionally been used in medicinal applications as an anti-inflammatory, anti-diarrheal, de-wormer, and for various types of pain management. Abstract. Common names include: awapuhi, bitter ginger, shampoo ginger (Malay = lempoyang) and pinecone ginger. It is native to India and Southeast Asia where it is often cultivated as a home garden plant. I went to eat some of the ginger and it was so intense! Now I get it watch it thrive and utilize the many flowers it creates!! Synonymes: * Zingiber aromaticum Valeton (1918) * Amomum zerumbet L. Ethymologie: Le terme Shampoo provient du liquide clair, visqueux-savonneux, à odeur de gingembre contenu dans les inflorescences. 4 Aquifoliaceae - Araliaceae - Aristolochiaceae - Asclepiadaceae. Basionym: Amomum zerumbet Linnaeus 1753. Matthes HWD, Luu B, Ourison G (1980) … Pinecone ginger (Zingiber zerumbet), which is also sometimes called shampoo ginger, produces showy, pinecone-shaped flower bracts. Zingiber zerumbet, ‘Awapuhi or Shampoo Ginger, is a perennial multipurpose herbaceous plant. Masuda T, Jitoe A, Kato S, Nakatani N (1991) Acetylated flavonol glycosides from Zingiber zerumbet. Flowering Plants of Hawaii. my hobby is all 42 year medicinal plants;,have so a 180 sort, as hobby;Iam 82 years old ;Iam looking after these plant ; awapuhi -kuahiwi >>>can jou help: Dig up rhizomes when dormant; divide and replant for plant replication in a separate area. : it’s generally not a problematic plant). Have you ever heard of anyone storing the mucilage long term? Check with your pharmacist for more details about the particular brand you use.The FDA has not reviewed this product for safety or effectiveness. Anti-Microbial - In this study they investigated antimicrobial effects of ethanolic extract of Zingiber zerumbet (Z. zerumbet) (L.) Smith and its chloroform and petroleum ether soluble fractions against pathogenic bacteria and fungi. I deduced that any herb that could have such an effect on hair, as well as fingernails (mine got much stronger on the powder) must have other wonderful effects on the body. Starr 020803-0013 Zingiber zerumbet.jpg 1,600 × 1,200; 423 KB. dear sir, A Floridata plant profile of species Zingiber zerumbet, commonly called pinecone ginger, shampoo ginger, Awapuhi kuahiwi (Hawaii) Home . Zingiber zerumbet (L.) Roscoe ex Sm. Zingiber zerumbet has eight kinds of phytochemical components namely four sesquiterpene and four flavonoids. I deduced that any herb that could have such an effect on hair, as well as fingernails (mine got much stronger on the powder) must have other wonderful effects on the body. The liquid from the inflorescence is drinkable. Zingiber spurium J.König. Rhizomatous herbs; stem upto 1.2 m tall. ive heard of people freezing it. Zingiber zerumbet Sm., locally known to the Malay as “Lempoyang,” is a perennial herb found in many tropical countries, including Malaysia. ‘Awaphui can form dense thickets, so allow them to have a lot of space, or plan to manage them annually. ZINGIBER ZERUMBET (Linnaeus) Smith, Exot. At a concentration of 400 µg/disc, all the samples showed mild to moderate antibacterial and antifungal activity and produced the zone of inhibition ranging from 6 mm to 10 mm. Zingiber zerumbet (L.) Smith belongs to the Zingiberaceae family that is widely distributed throughout the tropics, particularly in Southeast Asia. Type: INDIA: ** Not applicable or data not available. This plant is very carefree. Zingiber zerumbet (L.) Smith, from Zingiberaceae family is locally known to the Malay as 'lempoyang,' is a traditional herb found in many tropical countries, including Malaysia (Yob et al. Perhaps the most well known use for ‘awapuhi is the inflorescence liquid as shampoo or conditioner for the hair and skin, as it provides a soothing, shiny and smoothing effect. Ginger History. try it out! Articles & Resources . Mature rhizomes are intensely bitter; young rhizomes are not as powerful. TOXICITY AND THERAPEUTIC EFFECTS OF ZERUMBONE EXTRACT ON COMPLETE FREUND’S ADJUVANT-INDUCED RHEUMATOID ARTHRITIS RAT …, Synthesis and In Vitro Evaluation of Zerumbone Pendant Derivatives: Potent Candidates for Anti-Diabetic and Anti-Proliferative Activities, ANTIPROLIFERATIVE EFFECTS OF ZERUMBONE-HYDROXYPROPYL-β-CYCLODEXTRIN INCLUSION COMPLEX ON HepG2 LIVER CANCER CELLS In …, Efficacy of Channa Striatus Bloch Aqueous Extract and Zerumbone in Alleviating Induced Knee Osteoarthritis in Rats, CHARACTERIZATION OF CROSSLINKED ZERUMBONE LOADED GELATIN–ZEOLITE Y HYBRID COMPOSITES WITH GLUTARALDEHYDE FOR …, Zerumbone and Kaempferol Derivatives from the Rhizomes of Zingiber montanum (J. Koenig) Link ex A. Dietr. Awapuhi/Shampoo Ginger (Zingiber zerumbet). so yes ,what is the price + sent cost; Your email address will not be published. This ginger relative grows to heights of about two to four feet. for pharmaceutical and cosmeceutical industry, Molecular Mechanisms of Inhibitory Effect of Zerumbone on Human Malignant Melanoma Cells, Evaluation of cytotoxic and genotoxic effects of zerumbone on colon adenocarcinoma colo205 cells and human lymphocytes, Dietary zerumbone, a sesquiterpene, ameliorates hepatotoxin‐mediated acute and chronic liver injury in mice, Zerumbone Suppresses Human Colorectal Cancer Invasion and Metastasis via Modulation of FAk/PI3k/NFκB-uPA Pathway, Assessment of cell cycle phase-specific effects of zerumbone on mitotically synchronous surface cultures of Physarum polycephalum, Effects of zerumbone on proliferation and apoptosis of esophageal cancer cells and on P53 and Bcl-2 expression levels, Zerumbone, a sesquiterpene derived from tropical ginger, induces heme oxygenase-1 expression via activation of Nrf2 signaling in mouse epidermal cells and …, Inhibition Docking Simulation of Zerumbone, Gingerglycolipid B, and Curzerenone Compound of Zingiber zerumbet from Timor Island Against MurA Enzyme, Lewis‐Acid‐Catalyzed Activation of Zerumbone towards Sesquiterpenoid Derivatives: Sustainable Utilization of Abundant Natural Resources for the Synthesis of …, Stimulation of the ATPase activity of Hsp90 by zerumbone modification of its cysteine residues destabilizes its clients and causes cytotoxicity, Zerumbone, a cyclic sesquiterpene, exerts antimitotic activity in HeLa cells through tubulin binding and exhibits synergistic activity with vinblastine and paclitaxel, Anti-Leukemic Effects of Zerumbone Nanoparticle on Human Jurkat T Lymphoblastoid Cell Lines In Vitro and Murine Leukemic WEHI-3B Model In Vivo, Enhancing the effects of Zerumbone on THP-1 cell activation, Antitumor activity of Zerumbone in rhabdomyosarcoma, ffl ZERUMBONE: THE FASCINATING CHEMISTRY OF A MACROCYCLIC SESQUITERPENOID, The effect of ginger active component (Zerumbone) on human cancer cells, Conformation of the sesquiterpenoid zerumbone: X-ray crystallographic analysis of zerumbone 2, 4-dinitrophenylhydrazone, Metal-Free Trans-Aziridination of Zerumbone: Synthesis and Biological Evaluation of Aziridine Derivatives of Zerumbone, Beneficial effect of zerumbone on cholecystokinin-octapeptide-induced acute pancreatitis in rats, Isolation, characterization and modification of zerumbone from Zingiber zerumbet, Zerumbone promotes proliferation of endogenous neural stem cells in vascular dementia by regulating Notch signalling, Dose-Response Relationship of Zerumbone in Rat with Severe Acute Pancreatitis, Antinociceptive properties of zerumbone, a natural compound found in ginger, Nanoencapsulation of Zerumbone in Oleic Acid-Modified Chitosan Nanoparticles, Role of Zerumbone in the Chemosensitization of Cancer Cells, Exploring immunomodulatory and anticancer properties of zerumbone, Effects of zerumbone on the proliferation and apoptosis of human pancreatic cancer cell line PANC1, Molecular docking and molecular dynamics simulation of zerumbone derivatives with TGF-β1, Influence of different methods on the extraction of the zerumbone from Zingiber Zerumbet, Optimisation of Essential Oil Yield and Zerumbone Content in Zingiber Zerumbet Extract Using Hydrodistillation Process, Zerumbone inhibits Candida albicans biofilm formation and hyphal growth, Inhibitory effect of Zerumbone on migration of colorectal cancer cells via down-regulation of Matrix Metalloproteinase-13 (MMP-13), Cytotoxic Effects of Zerumbone on Ovarian and Cervical Cancer Cell Lines, Evaluation of urease inhibition activity of zerumbone in vitro, Modulation of survival and motility of colorectal cancer cell line by Zerumbone, Evaluation of Cytogenetic and DNA Damage Effects Induced by Zerumbone, Anti-biofilm and antimicrobial effects of zerumbone against Bacteroides fragilis, Zerumbone binding to estrogen receptors: an in-silico investigation, BIOTRANSFORMATION OF ZERUMBONE AND GONIOTHALAMIN, AND PHYTOCHEMICAL INVESTIGATION OF MARCHANTIA POLYMORPHA, Quantification of Zerumbone in Eleven Cultivars of Curcuma longa Using RP-HPLC, ZERUMBONE INHIBITS PROLIFERATION AND INDUCES APOPTOSIS, CELL CYCLE ARRESTIN HUMAN COLON CANCER CELLLINE, HCT15, Zerumbone in Combination with Curcumin FOR Probable Treatment in Liver Cancer, Anticancer Effect of Zerumbone-loaded nanostructured Lipid Carrier on Triple Negative Breast Cancer Cells, OPTIMIZATION OF HYDRODISTILLATION EXTRACTION CONDITIONS OF ZERUMBONE FROM ZINGIBER ZERUMBET RHIZOME, Zerumbone inhibits prostate cancer cell viability and induces cell death by non-apoptotic pathway, Virtual Screening of 1′-Acetoxychavicol Acetate, Zerumbone, Auraptene, and Nobiletin as Cyclooxygenase Isozymes Inhibitors, MODULATION OF SURVIVAL AND MOTILITY OF COLORECTAL CANCER CELL LINE BY ZERUMBONE, Proteomic and Genomic Evaluation of Zerumbone-Loaded Nanostructured Lipid Carrier in BALB/c Mice Model of Leukemia, Synthesis of important flavour and bioactive molecules from limonene and zerumbone, Immunological Evaluation of Zerumbone Loaded Nanostructured Lipid Carrier in BALB/c Mice Model of Leukemia, Development and In Vitro Evaluation of a Zerumbone Loaded Nanosuspension Drug Delivery System, Efficacy of zerumbone against dual-species biofilms of Candida albicans and Staphylococcus aureus, In Vitro Genotoxic effects of Zerumbone and Cisplatin Combination in CHO Cell lines, Effect of zerumbone on scopolamine‐induced memory impairment and anxiety‐like behaviours in rats, Zerumbone-Loaded Nanostructured Lipid Carrier Induces Apoptosis of Canine Mammary Adenocarcinoma Cells, Zerumbone, a Natural Dietary Sesquiterpene from Zingiber Zerumbet for Leukaemia Therapy In Vitro, Molecular Docking Analysis of 6-paradol, Zingerone and Zerumbone Against Human Estrogen Receptor Alpha (ERɑ), COMPUTATIONAL APPROACHES TO ELUCIDATE THE ACTION MECHANISM OF ZERUMBONE TOWARDS BETA CATENIN, PO-172 Zerumbone inhibits epithelial-mesenchymal transition and cancer stem cells properties by inhibiting β-catenin pathway through miR-200c, Zerumbone attenuates MPP+-induced cytotoxicity in human neuroblasto-ma SH-SY5Y cells by inhibition of oxidative stress, Antiproliferative Efficacy of Zerumbone-Loaded Nanostructured Lipid Carrier in BALB/c Mice Model of Breast Cancer, Cytotoxic and genotoxic effects of zerumbone on Wehi 7.2 wild type murine thymoma cells, Zerumbone from Zingiber zerumbet inhibits innate and adaptive immune responses in Balb/C mice, Dietary zerumbone from shampoo ginger: New insights into its antioxidant and anticancer activity, Dietary zerumbone from shampoo ginger: new insights into its antioxidant and anticancer activity, Enhancement and isolation of zerumbone in Zingiber zerumbet (L.) Smith cell suspension and adventitious root cultures/Mahanom Jalil, Repellency of zerumbone identified in Cyperus rotundus rhizome and other constituents to Blattella germanica, Zerumbone Suppresses Enterotoxigenic Bacteroides fragilis Infection-Induced Colonic Inflammation through Inhibition of NF-κΒ, Anti-metastatic Effects of Zerumbone-Loaded Nanostructured Lipid Carrier in Experimentally Induced Hepatocarcinoma in BALB/c Mice Model, Antileukemic Effect of Zerumbone-Loaded Nanostructured Lipid Carrier on Murine Leukemic (WEHI-3B) Model, Altered Cross-linking of HSP27 by Zerumbone as a Novel Strategy for Overcoming HSP27-mediated Resistance, Antiproliferative effects of zerumbone-pendant derivatives on human T-cell lymphoid cell line Jurkat cells, Molecular Mechanisms Underlying Chemopreventive Effects of Zerumbone, Curcumin and Phloretin on Mouse Skin Carcinogenesis, Zerumbone inhibits phorbol ester-induced intracellular ROS accumulation and neoplastic transformation by inducing Nrf2-driven heme oxygenase-1 expression in …, ANTI-ANGIOGENIC AND ANTI-HEPATOCELLULAR CARCINOMA PROPERTIES OF ZERUMBONE EXTRACTED FROM ZINGIBER ZERUMBET (L.) SMITH, Zerumbone, a natural plant dietary compound induces expression of interleukin-12P70 cytokine in human peripheral blood mononuclear cells, Docking studies reveal zerumbone targets β-catenin of the Wnt–β-catenin pathway in breast cancer. I used too much of it and made my meal unpalatable. Zerumbone was found to induce the apoptotic process in HepG2 cells through the up and down regulation of Bax/Bcl-2 protein independently of functional p53 activity. Perhaps the most well known use … Zingiber truncatum Stokes. RICH: Isolation and Characterization of Zerumbone, Effects of selected physicochemical parameters on zerumbone production of Zingiber zerumbet Smith cell suspension culture, Zerumbone induces gastric cancer cells apoptosis: Involving cyclophilin A, Zerumbone, a natural cyclic sesquiterpene of Zingiber zerumbet Smith, attenuates nonalcoholic fatty liver disease in hamsters fed on high-fat diet, Genotoxicity assessment of a natural anticancer compound zerumbone in CHO cell lines, Novel synthesis of zerumbone-pendant derivatives and their biological activity, Zerumbone suppresses the activation of inflammatory mediators in LPS-stimulated U937 macrophages through MyD88-dependent NF-κB/MAPK/PI3K-Akt signaling …, Zerumbone, a sesquiterpene, controls proliferation and induces cell cycle arrest in human laryngeal carcinoma cell line Hep-2, Antiallodynic and antihyperalgesic effects of zerumbone on a mouse model of chronic constriction injury-induced neuropathic pain, Antileukemic effect of zerumbone-loaded nanostructured lipid carrier in WEHI-3B cell-induced murine leukemia model, Biotransformation of zerumbone by Caragana chamlagu, Zerumbone significantly improved immunoreactivity in the synovium compared to Channa striatus extract in monosodium iodoacetate (MIA)-induced knee …, Binding mode analysis of zerumbone to key signal proteins in the tumor necrosis factor pathway, Possible contribution of zerumbone-induced proteo-stress to its anti-inflammatory functions via the activation of heat shock factor 1, Zerumbone reduced the inflammatory response of acute lung injury in endotoxin-treated mice via Akt-NFκB pathway, Zerumbone, a Cyclic Sesquiterpene from Zingiber zerumbet Induces Apoptosis, Cell Cycle Arrest, and Antimigratory Effects in SW480 Colorectal Cancer Cells, Zerumbone induces mitochondria-mediated apoptosis via increased calcium, generation of reactive oxygen species and upregulation of soluble histone H2AX in …, Comparison of apoptotic inducing effect of zerumbone and zerumbone-loaded nanostructured lipid carrier on human mammary adenocarcinoma MDA-MB-231 cell …, Optimization of microwave-assisted extraction of zerumbone from Zingiber zerumbet L. rhizome and evaluation of antiproliferative activity of optimized extracts, Effect of Zingiber zerumbet Essential Oils and Zerumbone Inhalation on Body Weight of Sprague Dawley Rat* I. Batubara,“I H. Suparto,” S. Sadiah,“R. All Rights Reserved. In an herbal supplement, one ingredient may provide the desired therapeutic benefits while others may have toxic effects for humans. Zingiber littorale (Valeton) Valeton. 1805. Also see: Which Foods Have More Vitamin C . In the next study they assessed the effects of zerumbone on cell proliferation activity of crypts by counting silver-stained nucleolar organizer regions protein (AgNORs) in colonic cryptal cell nuclei. Biomedical Properties of a Natural Dietary Plant Metabolite, Zerumbone, in Cancer Therapy and Chemoprevention Trials: A Review, Antiproliferative and antiangiogenic effects of zerumbone from Zingiber zerumbet L. Smith in sprague dawley rat model of hepatocellular carcinoma, Zerumbone Induces Apoptosis in Breast Cancer Cells by Targeting αvβ3 Integrin upon Co-Administration with TP5-iRGD Peptide, INHIBITORY EFFECT OF ZERUMBONE ON MIGRATION OF COLORECTAL CANCER CELLS VIA DOWN-REGULATION OF MATRIX METALLOPROTEINASE-13 …, Molecular docking, MD simulation, DFT and ADME-toxicity study on analogs of zerumbone against IKK-β enzyme as anti-cancer agents, Prophylactic and Therapeutic Efficacies of Dietary Zerumbone Supplementation on the Pathogenesis of Atherosclerosis in Cholesterol-fed Rabbits, ANTI-LEUKEMIC EFFECTS OF ZERUMBONE NANOPARTICLE ON HUMAN LYMPHOBLASTIC LEUKEMIA CELLS (JURKAT) IN VITRO AND MURINE …, Lewis-Acid-Catalyzed Activation of Zerumbone towards Sesquiterpenoid Derivatives: Sustainable Utilization of Abundant Natural Resources for the Synthesis of …, ANTI-ALLODYNIC AND ANTIHYPERALGESIC PROPERTIES OF ZERUMBONE AND THEIR MECHANISMS OF ACTION IN MICE MODEL OF NEUROPATHIC …, ANTI-ALLODYNIC AND ANTIHYPERALGESIC EFFECTS OF ZERUMBONE THROUGH INVOLVEMENT OF MONOAMINERGIC PATHWAYS IN MICE MODEL …, COMPARISON STUDY OF THE EFFECTS OF ZERUMBONE AND AG490 IN HUMAN RENAL CELL CARCINOMA ON THE ACTIVATION OF THE JANUS KINASE …, CYTOTOXICITY AND MECHANISMS OF ACTION OF ZERUMBONE-LOADED NANOSTRUCTURED LIPID CARRIER IN TRIPLE NEGATIVE BREAST CANCER …, ANTI-ALLODYNIC AND ANTIHYPERALGESIC ACTIVITIES OF ZERUMBONE IN CHRONIC CONSTRICTION INJURY-INDUCED NEUROPATHIC PAIN AND …, Potential chemoprevention of dimethylnitrosamine-initiated and 2-acetylaminofluorene-promoted hepatocarcinogenesis by zerumbone from the rhizomes of the …, … Obat Antikanker Payudara dari Lempuyang Gajah dan Lempuyang Emprit dengan Kontrol Kualitas Berbasis Senyawa Penanda Zerumbone dan Aktivitas Antikanker …, Zerumbone Protects against Carbon Tetrachloride (CCl4)-Induced Acute Liver Injury in Mice via Inhibiting Oxidative Stress and the Inflammatory Response: Involving …, … of ATF3 for ER Stress-induced Sensitization of p53-deficient Human Colon Cancer Cells to TRAIL-mediated Apoptosis Through Upregulation of DR5 by Zerumbone …, Study on transformation of zerumbone with fatty acid hydrazides, Hormetic Effects of Zerumbone in Proteostasis, Zerumbone 처리에 따른 Helicobacter pylori 의 단백질 비교분석, CYTOTOXICTY OF ZERUMBONE AGAINST LIVER CANCER CELL LINES (HepG2) VIA APOPTOSIS ACTIVITY, Comparative Proteome Analysis of Zerumbone-treated Helicobacter pylori, Nghiên cứu các phương pháp phân lập Zerumbone có chất lượng cao từ thân rễ cây gừng gió (zingiber zerumbert sm.) The rhizomes of Z. zerumbet, particularly, have been regularly used as food flavouring and appetizer in various Malays' cuisines while the rhizomes extracts have been used in Malay traditional medicine to treat various types of ailments (e.g., inflammatory- and pain-mediated diseases, worm infestation and diarrhea). The results indicate that ZER is a food phytochemical that has distinct potentials for use in anti-inflammation, chemoprevention, and chemotherapy strategies. If using as shampoo, you may or may not decide to rinse out the liquid dependent upon your desires. is an accepted name This name is the accepted name of a species in the genus Zingiber (family Zingiberaceae ). Zingiber zerumbet: Taxonomy navigation › Zingiber. The liquid from the inflorescence is drinkable. This study evaluated in vitro antioxidant potential of Z. zerumbet rhizome ethyl acetate extract on hydrogen peroxide (H 2 O 2)-induced red blood cells (RBCs) damage; by measuring percentage of haemolysis, oxidative damage and Zingiber aromaticum Valeton. The record derives from WCSP (data supplied on 2012-03-26 ) which reports it as an accepted name (record 273442 ) with original publication details: Exot. Zerumbone suppresses osteopontin-induced cell invasion through inhibiting the FAK/AKT/ROCK pathway in human non-small cell lung cancer A549 cells, Zerumbone, a phytochemical of subtropical ginger, protects against hyperglycemia-induced retinal damage in experimental diabetic rats, Zerumbone protects INS-1 rat pancreatic beta cells from high glucose-induced apoptosis through generation of reactive oxygen species, Anticancer activity of the bioreductive and non-bioreductive zerumbone derivatives, Zerumbone inhibits melanoma cell proliferation and migration by altering mitochondrial functions, Development and validation of an HPTLC method for analysis of zerumbone, the anticancer marker from Zingiber zerumbet, Zerumbone suppresses the motility and tumorigenecity of triple negative breast cancer cells via the inhibition of TGF-β1 signaling pathway, Zerumbone, a ginger sesquiterpene, induces apoptosis and autophagy in human hormone-refractory prostate cancers through tubulin binding and crosstalk between …, Promotion of p53 expression and reactive oxidative stress production is involved in zerumbone-induced cisplatin sensitization of non-small cell lung cancer cells, Protective effect of zerumbone reduces lipopolysaccharide-induced acute lung injury via antioxidative enzymes and Nrf2/HO-1 pathway, Inclusion complex of zerumbone with hydroxypropyl-β-cyclodextrin induces apoptosis in liver hepatocellular HepG2 cells via caspase 8/bid cleavage switch and …, Elevated IL-1β expression induces invasiveness of triple negative breast cancer cells and is suppressed by zerumbone, Zerumbone suppresses EGF-induced CD44 expression through the inhibition of STAT3 in breast cancer cells, A review of the biomedical applications of zerumbone and the techniques for its extraction from ginger rhizomes, Contribution to the Study of Essential Oil of Xylopia Aethiopica (DUNAL) A. Rhizomes spread on their own naturally. “Zingiber” is originally from a Sanskrit word that means “shaped like a horn” and refers to the horn-shaped leaves of most species of ginger. Leaves 15-35 x 4-7.5 cm, oblong or oblong-lanceolate, base obtuse, apex acuminate, pubescent below; ligule to 2.5 cm long. Shoots are spicy and consist of the still folded leaves as they emerge. 1. ANTI-ACNE EFFECT OF FLAVONOIDS AND POLYPHENOLS, ANTI-AGING EFFECTS OF FLAVONOIDS & POLYPHENOLS, ANTI-CANCER EFFECTS OF FLAVONOIDS & POLYPHENOLS, ANTI-INFLAMMATORY EFFECTS OF FLAVONOIDS & POLYPHENOLS, ANTI-VIRAL EFFECTS OF FLAVONOIDS & POLYPHENOLS, FASTING, CALORIE RESTRICTION & EXTENDING LIFESPAN, JNK ACTIVATION PREVENTS PREMATURE SENESCENCE, NRF2: MASTER REGULATOR OF THE AGING PROCESS, SENESCENCE-BETA-GALACTOSIDASE (SA-β-gal or SABG), INTERSTELLAR 88/8: EXTREME WEIGHTLOSS PROTOCOL, Zerumbone, a tropical ginger sesquiterpene, activates phase II drug metabolizing enzymes, Zerumbone, a tropical ginger sesquiterpene, inhibits colon and lung carcinogenesis in mice, Zerumbone induced apoptosis in liver cancer cells via modulation of Bax/Bcl-2 ratio, Antitumor activity of extract of Zingiber aromaticum and its bioactive sesquiterpenoid zerumbone, Studies in sesquiterpenes—XVI: Zerumbone, a monocyclic sesquiterpene ketone, Zerumbone, a sesquiterpene in subtropical ginger, suppresses skin tumor initiation and promotion stages in ICR mice, Anti-inflammatory effect of zerumbone on acute and chronic inflammation models in mice, Chemoprevention of azoxymethane-induced rat aberrant crypt foci by dietary zerumbone isolated from Zingiber zerumbet, Zerumbone induces apoptosis in T-acute lymphoblastic leukemia cells, In vitro ultramorphological assessment of apoptosis induced by zerumbone on (HeLa), Zerumbone-loaded nanostructured lipid carriers: preparation, characterization, and antileukemic effect, Zerumbone, an HIV-inhibitory and cytotoxic sesquiterpene of Zingiber aromaticum and Z. zerumbet, Anticancer and antimicrobial activities of zerumbone from, Characterization of the inclusion complex of zerumbone with hydroxypropyl-β-cyclodextrin, Chemistry of zerumbone. 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